Cytokeratin 1 anticorps (Middle Region)

N° du produit ABIN2775333

L’anticorps Lapin Polyclonal anti-Cytokeratin 1 a été validé pour WB et IHC. Il convient pour détecter Cytokeratin 1 dans des échantillons de Humain, Rat, Lapin et Chien.

Aperçu rapide pour Cytokeratin 1 anticorps (Middle Region) (ABIN2775333)

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivité: Humain, Rat, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytokeratin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Cytokeratin 1 anticorps

Épitope: Middle Region

Séquence: GSYGSGSSSG GYRGGSGGGG GGSSGGRGSG GGSSGGSIGG RGSSSGGVKS

Homologie: Dog: 86%, Human: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against KRT1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KRT1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 644 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Cytokeratin 1

Antigène: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Autre désignation: KRT1

Sujet: KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CK1, EHK1, K1, KRT1A, EHK, EPPK, NEPPK
Protein Interaction Partner: MDM2, LGR4, EED, ESR1, ADRB2, PAN2, Iqcb1, Nphp4, Cep290, Nphp1, Invs, GRDX, VCAM1, UBC, ITGA4, FN1, CDH1, APOA1, ALB, MAGOH, EIF4A3, KRT10, KRT9, KRT2, SLC25A5, SHC1, PIK3R2, INPPL1, GRB2, EPS15, CRK, AP2M1, CBL, UBASH3B, NEDD8, CAND1, DCUN1D1, COPS5, CO
Protein Size: 644

Poids moléculaire: 66 kDa

ID gène: 3848

NCBI Accession: NM_006121, NP_006112

UniProt: P04264