ESRP2 anticorps (C-Term)
Aperçu rapide pour ESRP2 anticorps (C-Term) (ABIN2775446)
Antigène
Voir toutes ESRP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- LLPAARVPAA ATPLAYYPGP ATQLYMNYTA YYPSPPVSPT TVGYLTTPPT
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Homologie
- Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against Esrp2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide corresponding to a region of Mouse
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 717 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))
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Autre désignation
- Esrp2
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Sujet
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Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Alias Symbols: 9530027K23Rik, Rbm35b
Protein Size: 717 -
Poids moléculaire
- 77 kDa
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ID gène
- 77411
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NCBI Accession
- NM_176838, NP_789808
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UniProt
- Q8K0G8
Antigène
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