ESRP2 anticorps (C-Term)

N° du produit ABIN2775446

Détail du produit anti-ESRP2 anticorps

Antigène: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ESRP2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LLPAARVPAA ATPLAYYPGP ATQLYMNYTA YYPSPPVSPT TVGYLTTPPT

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Esrp2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 717 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ESRP2

Antigène: ESRP2 (Epithelial Splicing Regulatory Protein 2 (ESRP2))

Autre désignation: Esrp2 (ESRP2 Produits)

Synonymes: anticorps RBM35B, anticorps 9530027K23Rik, anticorps Rbm35b, anticorps RGD1310855, anticorps cb404, anticorps fa07a06, anticorps rbm35b, anticorps sb:cb404, anticorps zgc:77254, anticorps epithelial splicing regulatory protein 2, anticorps microRNA 6773, anticorps ESRP2, anticorps Esrp2, anticorps MIR6773, anticorps esrp2

Sujet: Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Alias Symbols: 9530027K23Rik, Rbm35b
Protein Size: 717

Poids moléculaire: 77 kDa

ID gène: 77411

NCBI Accession: NM_176838, NP_789808

UniProt: Q8K0G8