DNASE2B anticorps (N-Term)

N° du produit ABIN2775490

Cet anticorps Lapin Polyclonal détecte spécifiquement DNASE2B dans WB. Il présente une réactivité envers Humain, Cobaye, Boeuf (Vache), Cheval, Rat, Chien et Lapin.

Aperçu rapide pour DNASE2B anticorps (N-Term) (ABIN2775490)

Antigène: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Reactivité: Humain, Cobaye, Boeuf (Vache), Cheval, Rat, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNASE2B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DNASE2B anticorps

Épitope: N-Term

Séquence: EGKAVDWFTF YKLPKRQNKE SGETGLEYLY LDSTTRSWRK SEQLMNDTKS

Homologie: Cow: 79%, Dog: 82%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DNASE2B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DNASE2B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 357 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DNASE2B

Antigène: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Autre désignation: DNASE2B

Sujet: DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: DLAD
Protein Interaction Partner: UBC, UBD,
Protein Size: 357

Poids moléculaire: 39 kDa

ID gène: 58511

NCBI Accession: NM_021233, NP_067056

UniProt: Q8WZ79