DNASE2B anticorps (Middle Region)

N° du produit ABIN405485

L’anticorps anti-DNASE2B Polyclonal Lapin est utilisé pour la détection de DNASE2B dans des échantillons de Humain, Cobaye, Rat, Boeuf (Vache), Cheval et Porc. Il a été validé pour WB.

Aperçu rapide pour DNASE2B anticorps (Middle Region) (ABIN405485)

Antigène: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Reactivité: Humain, Cobaye, Rat, Boeuf (Vache), Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNASE2B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DNASE2B anticorps

Épitope: Middle Region

Fonction: DNASE2B Antibody - middle region

Séquence: IKAIKLSRHS YFSSYQDHAK WCISQKGTKN RWTCIGDLNR SPHQAFRSGG

Homologie: Cow: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against DNASE2B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DNASE2B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42596-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DNASE2B

Antigène: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Autre désignation: DNASE2B

Sujet:

Background Information: DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

Gene Name: Deoxyribonuclease II beta

Alternative Symbols: DLAD

Protein Name: Deoxyribonuclease-2-beta

Poids moléculaire: 39kDa

ID gène: 58511

NCBI Accession: NP_067056

UniProt: Q8WZ79