RFFL anticorps (Middle Region)

N° du produit ABIN2775666

Cité dans 1 publication. Cet anticorps anti-RFFL Polyclonal Lapin (ABIN2775666) détecte spécifiquement RFFL dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Lapin et Cobaye.

Aperçu rapide pour RFFL anticorps (Middle Region) (ABIN2775666)

Antigène: RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFFL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RFFL anticorps

Épitope: Middle Region

Fonction: RFFL Antibody - middle region

Séquence: KDQKGLQHLV SGAEDQNGGA VPSGLEENLC KICMDSPIDC VLLECGHMVT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RFFL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RFFL

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42986-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RFFL (ABIN2775666)

Hanuszkiewicz, Pittock, Humphries, Moll, Rosales, Molinaro, Moynagh, Lajoie, Valvano: "Identification of the flagellin glycosylation system in Burkholderia cenocepacia and the contribution of glycosylated flagellin to evasion of human innate immune responses." dans: The Journal of biological chemistry, Vol. 289, Issue 27, pp. 19231-44, (2014) (PubMed).

Détails sur RFFL

Antigène: RFFL (Ring Finger and FYVE-Like Domain Containing 1 (RFFL))

Autre désignation: RFFL

Sujet:

Background Information: RFFL has E3 ubiquitin protein ligase activity.RFFL regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity.RFFL may bind phosphatidylinositol phosphates.

Gene Name: Ring finger and FYVE-like domain containing E3 ubiquitin protein ligase

Alternative Symbols: CARP2, FRING, CARP-2, RNF189, RNF34L, RIFIFYLIN

Protein Name: E3 ubiquitin-protein ligase rififylin

Poids moléculaire: 40kDa

ID gène: 117584

NCBI Accession: NP_001017368

UniProt: Q8WZ73