UBE2I anticorps (N-Term)

N° du produit ABIN2775680

Cet anticorps Lapin Polyclonal détecte spécifiquement UBE2I dans WB. Il présente une réactivité envers Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Lapin, Cheval et Cobaye.

Aperçu rapide pour UBE2I anticorps (N-Term) (ABIN2775680)

Antigène: UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2I est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UBE2I anticorps

Épitope: N-Term

Séquence: MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2I. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2I

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 158 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBE2I

Antigène: UBE2I (Ubiquitin-Conjugating Enzyme E2I (UBE2I))

Autre désignation: UBE2I

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2I is a member of the E2 ubiquitin-conjugating enzyme family.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: C358B7.1, P18, UBC9
Protein Interaction Partner: TRIM21, SP100, SUMO2, RANGAP1, PTEN, LMO2, PIAS2, TRIM23, PARP1, PIAS4, UBXN1, USP25, SETBP1, SIRT1, PUF60, HMGA1, GOLGA2, FHL3, ELK1, DES, DAXX, CREBBP, CLK2, RCBTB2, CEBPD, CBS, CAPN2, PPARGC1A, RFPL3, TRIM38, IKZF1, RNF40, XBP1, KRT19, HNRNPC, ZBTB8A,
Protein Size: 158

Poids moléculaire: 17 kDa

ID gène: 7329

NCBI Accession: NM_003345, NP_003336

UniProt: P63279

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Ubiquitin Proteasome Pathway