UBE2L6 anticorps (N-Term)
Aperçu rapide pour UBE2L6 anticorps (N-Term) (ABIN2775687)
Antigène
Voir toutes UBE2L6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- LLLPDQPPYH LKAFNLRISF PPEYPFKPPM IKFTTKIYHP NVDENGQICL
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Homologie
- Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 85%, Zebrafish: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against UBE2L6. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2L6
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 153 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8." dans: Molecular and cellular biochemistry, Vol. 288, Issue 1-2, pp. 151-7, (2006) (PubMed).
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: "The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8." dans: Molecular and cellular biochemistry, Vol. 288, Issue 1-2, pp. 151-7, (2006) (PubMed).
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- UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
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Autre désignation
- UBE2L6
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Sujet
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: MGC40331, RIG-B, UBCH8
Protein Interaction Partner: LONRF1, FBXO31, RBCK1, ARIH2, RBX1, CUL1, SKP1, UBE2L6, UBC, SIAH2, PARK2, RNF144A, UBE3A, RAD23A, ARIH1, SPEN, ISG15, TIMM8A, RAD21, FLT3, ARHGDIA, park, SIAH1, RUNX1, RNF144B, DTX3, RNF19B, TRAF7, TRIM8, RNF122, MUL1, RNF25, RNF150, RNF125, CBLC, TOPORS
Protein Size: 153 -
Poids moléculaire
- 18 kDa
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ID gène
- 9246
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NCBI Accession
- NM_004223, NP_004214
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UniProt
- Q8N5D8
Antigène
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