UBE2L6 anticorps (N-Term)

N° du produit ABIN2775687

Il existe 1 publication pour ce produit. L’anticorps anti-UBE2L6 Polyclonal Lapin est utilisé pour la détection de UBE2L6 dans des échantillons de Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour UBE2L6 anticorps (N-Term) (ABIN2775687)

Antigène: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Reactivité: Humain, Rat, Souris, Porc, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2L6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UBE2L6 anticorps

Épitope: N-Term

Fonction: UBE2L6 Antibody - N-terminal region

Séquence: LLLPDQPPYH LKAFNLRISF PPEYPFKPPM IKFTTKIYHP NVDENGQICL

Homologie: Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 85%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2L6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2L6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43033-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-UBE2L6 (ABIN2775687)

Li, Wang, Yang, Li, Qin, Dong, Zhu, Liang, Liang, Han: "The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8." dans: Molecular and cellular biochemistry, Vol. 288, Issue 1-2, pp. 151-7, (2006) (PubMed).

Détails sur UBE2L6

Antigène: UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))

Autre désignation: UBE2L6

Sujet:

Background Information: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: Ubiquitin-conjugating enzyme E2L 6

Alternative Symbols: RIG-B, UBCH8

Protein Name: Ubiquitin/ISG15-conjugating enzyme E2 L6

Poids moléculaire: 18kDa

ID gène: 9246

NCBI Accession: NP_004214

UniProt: Q8N5D8