CCT4 anticorps (C-Term)

N° du produit ABIN2775694

Il existe 2+ publications pour ce produit. L’anticorps anti-CCT4 Polyclonal Lapin est utilisé pour la détection de CCT4 dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin et Saccharomyces cerevisiae. Il a été validé pour WB et IHC.

Aperçu rapide pour CCT4 anticorps (C-Term) (ABIN2775694)

Antigène: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCT4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CCT4 anticorps

Épitope: C-Term

Fonction: CCT4 Antibody - C-terminal region

Séquence: AFADAMEVIP STLAENAGLN PISTVTELRN RHAQGEKTAG INVRKGGISN

Homologie: Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CCT4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CCT4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34271-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CCT4 (ABIN2775694)

Tarkar, Loges, Slagle, Francis, Dougherty, Tamayo, Shook, Cantino, Schwartz, Jahnke, Olbrich, Werner, Raidt, Pennekamp, Abouhamed, Hjeij, Köhler, Griese, Li, Lemke, Klena, Liu, Gabriel, Tobita et al.: "DYX1C1 is required for axonemal dynein assembly and ciliary motility. ..." dans: Nature genetics, Vol. 45, Issue 9, pp. 995-1003, (2013) (PubMed).

Machida, Masutani, Kobayashi, Mikami, Nishino, Miyazawa, Imataka: "Reconstitution of the human chaperonin CCT by co-expression of the eight distinct subunits in mammalian cells." dans: Protein expression and purification, Vol. 82, Issue 1, pp. 61-9, (2012) (PubMed).

Détails sur CCT4

Antigène: CCT4 (Chaperonin Containing TCP1, Subunit 4 (Delta) (CCT4))

Autre désignation: CCT4

Sujet:

Targeted Subunit: delta

Background Information: The CCT (chaperonin containing TCP-1) complex functions as a molecular chaperone in the eukaryotic cytosol. CCT4 interacts with human cyclin E which has been implicated in positive control of the G1/S phase transition.

Gene Name: Chaperonin containing TCP1, subunit 4 (delta)

Alternative Symbols: SRB, Cctd, CCT-DELTA

Protein Name: T-complex protein 1 subunit delta

Poids moléculaire: 58kDa

ID gène: 10575

NCBI Accession: NP_006421

UniProt: Q53QP9

Pathways: Embryonic Body Morphogenesis