CHD4 anticorps (N-Term)
Aperçu rapide pour CHD4 anticorps (N-Term) (ABIN2775753)
Antigène
Voir toutes CHD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- QKKERMLLCR QLGDSSGEGP EFVEEEEEVA LRSDSEGSDY TPGKKKKKKL
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CHD4. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CHD4
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1912 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))
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Autre désignation
- CHD4
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Sujet
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CHD4 is a probable transcription regulator.The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp686E06161, Mi-2b, Mi2-BETA
Protein Interaction Partner: SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, UBC, LGR4, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, BMI1, GATAD2A, HDAC2, HDAC1, MTA3, CSNK2A1, HIST3H3, VCAM1, ITGA4, NOTCH1, ESR1, TBL1XR1, MBD3, MTA2, SMARCC1, RBBP7, RBBP4, CHD3, SNAI1, SNAI2, SUMO1, NEDD8, MTA1, NR2C2,
Protein Size: 1912 -
Poids moléculaire
- 218 kDa
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ID gène
- 1108
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NCBI Accession
- NM_001273, NP_001264
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UniProt
- Q14839
Antigène
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