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ATG4B anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-ATG4B a été validé pour WB et IHC. Il convient pour détecter ATG4B dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Cobaye, Lapin, Boeuf (Vache) et Cheval.
N° du produit ABIN2775793

Aperçu rapide pour ATG4B anticorps (C-Term) (ABIN2775793)

Antigène

Voir toutes ATG4B Anticorps
ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reactivité

  • 105
  • 52
  • 29
  • 7
  • 6
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Cobaye, Lapin, Boeuf (Vache), Cheval

Hôte

  • 102
  • 5
Lapin

Clonalité

  • 99
  • 8
Polyclonal

Conjugué

  • 53
  • 7
  • 7
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ATG4B est non-conjugé

Application

  • 81
  • 34
  • 23
  • 15
  • 13
  • 13
  • 13
  • 11
  • 11
  • 7
  • 3
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 20
    • 17
    • 15
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Séquence

    LGGALPMFEL VELQPSHLAC PDVLNLSLDS SDVERLERFF DSEDEDFEIL

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

    Attributs du produit

    This is a rabbit polyclonal antibody against APG4B. It was validated on Western Blot and immunohistochemistry.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human APG4B
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 393 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

    Autre désignation

    APG4B

    Sujet

    Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.
    Alias Symbols: APG4B, AUTL1
    Protein Interaction Partner: SUMO2, MAP1LC3B, MAP1LC3A, BAG3, ATG8, YWHAB, GABARAPL1, SQSTM1, UBC, GABARAPL2, ATG10, ATG3, AMBRA1, GABARAP, CAMKK2, ATG12, ULK1, STK3, KRT4, ANXA1, FBXW11, LINC00341,
    Protein Size: 393

    Poids moléculaire

    44 kDa

    ID gène

    23192

    NCBI Accession

    NM_013325, NP_037457

    UniProt

    Q9Y4P1

    Pathways

    Autophagy
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