LIMA1 anticorps (Middle Region)

N° du produit ABIN2775866

Cet anticorps Lapin Polyclonal détecte spécifiquement LIMA1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Cheval, Boeuf (Vache), Chien et Cobaye et a été mentionné dans 1 publication.

Aperçu rapide pour LIMA1 anticorps (Middle Region) (ABIN2775866)

Antigène: LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))

Reactivité: Humain, Souris, Rat, Lapin, Cheval, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIMA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LIMA1 anticorps

Épitope: Middle Region

Séquence: GVLAASMEAK ASSQQEKEDK PAETKKLRIA WPPPTELGSS GSALEEGIKM

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 92%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against LIMA1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human LIMA1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 759 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-LIMA1 (ABIN2775866)

Maul, Song, Amann, Gerbin, Pollard, Chang: "EPLIN regulates actin dynamics by cross-linking and stabilizing filaments." dans: The Journal of cell biology, Vol. 160, Issue 3, pp. 399-407, (2003) (PubMed).

Détails sur LIMA1

Antigène: LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))

Autre désignation: LIMA1

Sujet: This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.
Alias Symbols: EPLIN, SREBP3
Protein Interaction Partner: TP53, UBC, RPA3, RPA2, RPA1, SUZ12, RNF2, EZH2, BMI1, LRCH3, YWHAQ, YWHAB, PAN2, YWHAE, FMNL1, PAXIP1, ATP6V1B1, APP, UBXN6, LRRK2, ARRB2, ARRB1, SVIL, YWHAG,
Protein Size: 759

Poids moléculaire: 85 kDa

ID gène: 51474

NCBI Accession: NM_016357, NP_057441

UniProt: Q9UHB6