KCNIP4 anticorps (N-Term)

N° du produit ABIN2775914

Cet anticorps Lapin Polyclonal détecte spécifiquement KCNIP4 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin et Chien.

Aperçu rapide pour KCNIP4 anticorps (N-Term) (ABIN2775914)

Antigène: KCNIP4 (Kv Channel Interacting Protein 4 (KCNIP4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNIP4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KCNIP4 anticorps

Épitope: N-Term

Séquence: NVRRVESISA QLEEASSTGG FLYAQNSTKR SIKERLMKLL PCSAAKTSSP

Homologie: Cow: 93%, Dog: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against KCNIP4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNIP4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 250 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KCNIP4

Antigène: KCNIP4 (Kv Channel Interacting Protein 4 (KCNIP4))

Autre désignation: KCNIP4

Sujet: KCNIP4 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: CALP, KCHIP4, MGC44947
Protein Interaction Partner: APP, KCND2, PSEN2, PSEN1, KCNIP2,
Protein Size: 250

Poids moléculaire: 29 kDa

ID gène: 80333

NCBI Accession: NM_025221, NP_079497

UniProt: Q6PIL6