TRIOBP anticorps (Middle Region)

N° du produit ABIN2775973

L’anticorps Lapin Polyclonal anti-TRIOBP a été validé pour WB et IHC. Il convient pour détecter TRIOBP dans des échantillons de Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye, Lapin, Chien et Porc.

Aperçu rapide pour TRIOBP anticorps (Middle Region) (ABIN2775973)

Antigène: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye, Lapin, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIOBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TRIOBP anticorps

Épitope: Middle Region

Séquence: QIHTKDAVYT LSAMTSGIRR NWIEALRKTV RPTSAPDVTK LSDSNKENAL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against TRIOBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TRIOBP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 431 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRIOBP

Antigène: TRIOBP (TRIO and F-Actin Binding Protein (TRIOBP))

Autre désignation: TRIOBP

Sujet: TRIOBP is a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness.This gene encodes a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio-binding protein also associates with F-actin and stabilizes F-actin structures. Domains contained in this encoded protein are an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
Alias Symbols: DFNB28, FLJ39315, HRIHFB2122, KIAA1662, TARA, dJ37E16.4
Protein Interaction Partner: POLR1C, IKBKG, GTF2H1, PLK1, ELAVL1, VIM, HECTD3, UBC,
Protein Size: 431

Poids moléculaire: 47 kDa

ID gène: 11078

NCBI Accession: NM_138632, NP_619538

UniProt: Q9H2D6

Pathways: Regulation of Actin Filament Polymerization