CBX3 anticorps (Middle Region)

N° du produit ABIN2775975

L’anticorps Lapin Polyclonal anti-CBX3 a été validé pour WB. Il convient pour détecter CBX3 dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval et Lapin.

Aperçu rapide pour CBX3 anticorps (Middle Region) (ABIN2775975)

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CBX3 anticorps

Épitope: Middle Region

Séquence: WEPEENLDCP ELIEAFLNSQ KAGKEKDGTK RKSLSDSESD DSKSKKKRDA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CBX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CBX3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 183 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CBX3

Antigène: CBX3 (Chromobox Homolog 3 (CBX3))

Autre désignation: CBX3

Sujet: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. CBX3 binds DNA and is a component of heterochromatin. CBX3 also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of CBX3 may explain the association of heterochromatin with the inner nuclear membrane.At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
Alias Symbols: HECH, HP1-GAMMA, HP1Hs-gamma
Protein Interaction Partner: UBC, SUMO1, MDM2, EED, SUZ12, RNF2, WDR1, DCK, ADSS, THOP1, TALDO1, PTMS, OXCT1, IDH1, HSPE1, HECW2, PARK2, VHL, CHAF1A, AURKB, AURKA, EHMT2, FN1, TRIM39, HNF1A, CBX5, MDC1, TP53BP1, YWHAE, TNKS1BP1, H2AFY, ATXN7L2, CACNB4, BAHD1, CUL1, PCGF6, SIRT7, RYBP
Protein Size: 183

Poids moléculaire: 21 kDa

ID gène: 11335

NCBI Accession: NM_007276, NP_009207

UniProt: Q13185