KCNJ5 anticorps (N-Term)

N° du produit ABIN2776123

Détail du produit anti-KCNJ5 anticorps

Antigène: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Lapin, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNJ5 est non-conjugé

Application: Western Blotting (WB)

Séquence: AGDSRNAMNQ DMEIGVTPWD PKKIPKQARD YVPIATDRTR LLAEGKKPRQ

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against KCNJ5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNJ5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 419 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KCNJ5

Antigène: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Autre désignation: KCNJ5 (KCNJ5 Produits)

Synonymes: anticorps CIR, anticorps GIRK4, anticorps KATP1, anticorps KIR3.4, anticorps LQT13, anticorps Kir3.4, anticorps GIRK-4, anticorps KATP-1, anticorps potassium voltage-gated channel subfamily J member 5, anticorps potassium inwardly-rectifying channel, subfamily J, member 5, anticorps KCNJ5, anticorps Kcnj5

Sujet: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. KCNJ5 is an integral membrane protein and inward-rectifier type potassium channel. KCNJ5, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. Sequence Note: The sequence U52154.1 is a chimeric mRNA clone. Only the potassium inwardly-rectifying channel, subfamily J, member 5 region was propagated into this RefSeq record. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CIR, GIRK4, KATP1, KIR3.4, LQT13
Protein Interaction Partner: KCNJ5, KCNJ3, DRD4, DRD2, ADRB2,
Protein Size: 419

Poids moléculaire: 48 kDa

ID gène: 3762

NCBI Accession: NM_000890, NP_000881

UniProt: P48544

Pathways: Signalisation Notch