GABRQ anticorps (N-Term)

N° du produit ABIN2776224

Cité dans 1 publication. Cet anticorps anti-GABRQ Polyclonal Lapin (ABIN2776224) détecte spécifiquement GABRQ dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval et Porc.

Aperçu rapide pour GABRQ anticorps (N-Term) (ABIN2776224)

Antigène: GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABRQ est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GABRQ anticorps

Épitope: N-Term

Fonction: GABRQ Antibody - N-terminal region

Séquence: KFHFEFSSAV PEVVLNLFNC KNCANEAVVQ KILDRVLSRY DVRLRPNFGG

Homologie: Cow: 87%, Dog: 87%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GABRQ. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GABRQ

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101293

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GABRQ (ABIN2776224)

Fatemi, Folsom, Rooney, Thuras: "mRNA and protein expression for novel GABAA receptors ? and ?2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway." dans: Translational psychiatry, Vol. 3, pp. e271, (2013) (PubMed).

Détails sur GABRQ

Antigène: GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))

Autre désignation: GABRQ

Sujet:

Targeted Subunit: theta

Background Information: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. GABRQ gene is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases:early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, theta subunit. It is mapped to chromosome Xq28 in a cluster including the genes encoding the alpha 3 and epsilon subunits of the same receptor. This gene location is also the candidate region of 2 different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3).

Gene Name: Gamma-aminobutyric acid (GABA) A receptor, theta

Alternative Symbols: THETA

Protein Name: Gamma-aminobutyric acid receptor subunit theta

Poids moléculaire: 72kDa

ID gène: 55879

NCBI Accession: NP_061028

UniProt: Q9UN88