TBPL1 anticorps (Middle Region)
Aperçu rapide pour TBPL1 anticorps (Middle Region) (ABIN2776432)
Antigène
Voir toutes TBPL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- LQKLGFQVIF TDFKVVNVLA VCNMPFEIRL PEFTKNNRPH ASYEPELHPA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against TBPL1. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TBPL1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 186 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TBPL1 (TBP-Like 1 (TBPL1))
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Autre désignation
- TBPL1
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Sujet
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TBPL1 encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
Alias Symbols: TLF, TLP, STUD, TRF2, MGC:8389, MGC:9620
Protein Interaction Partner: TNNT1, FUS, APP, PRNP, ELAVL1, UBC, TERF2, TERF1, TBPL2, TAF1L, TBP, TAF6, TAF5, TAF4, TAF1, HSPA9, GTF2A2, GTF2A1, SLC35F6, ABCF3, NDUFA6, GTF2B, PTCD3, IRAK4, RAB35, PLIN3, RPL10, NF1, PMVK,
Protein Size: 186 -
Poids moléculaire
- 21 kDa
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ID gène
- 9519
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NCBI Accession
- NM_004865, NP_004856
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UniProt
- P62380
Antigène
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