L3MBTL1 anticorps (N-Term)

N° du produit ABIN2776522

Détail du produit anti-L3MBTL1 anticorps

Antigène: L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

Épitope: N-Term

Reactivité: Humain, Cobaye, Chien, Rat, Lapin, Cheval, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L3MBTL1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LLKPMKKRKR REYQSPSEEE SEPEAMEKQE EGKDPEGQPT ASTPESEEWS

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Rabbit: 79%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against L3MBTL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human L3MBTL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 772 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur L3MBTL1

Antigène: L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))

Autre désignation: L3MBTL (L3MBTL1 Produits)

Synonymes: anticorps C630004G01, anticorps L3mbtl, anticorps mKIAA0681, anticorps H-L(3)MBT, anticorps L3MBTL, anticorps ZC2HC3, anticorps dJ138B7.3, anticorps RGD1307316, anticorps l(3)mbt-like (Drosophila), anticorps L3MBTL1, histone methyl-lysine binding protein, anticorps l(3)mbt-like 1 (Drosophila), anticorps L3mbtl1, anticorps L3MBTL1

Sujet: L3MBTL is the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. L3MBTL is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells.This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DKFZp586P1522, FLJ41181, H-L(3)MBT, KIAA0681, L3MBTL1, dJ138B7.3, L3MBTL
Protein Interaction Partner: VCP, UBC, PCNA, MCM7, MCM6, MCM5, MCM4, MCM3, CDC45, MCM2, SETD8, TP53, HIST1H1E, L3MBTL1, ETV7, ETV6, HIST2H4A, CBX3, RB1, HIST1H1B, SETD7, CBX5,
Protein Size: 772

Poids moléculaire: 86 kDa

ID gène: 26013

NCBI Accession: NM_015478, NP_056293

UniProt: Q9Y468

Pathways: Chromatin Binding