UPF3A anticorps (Middle Region)
Aperçu rapide pour UPF3A anticorps (Middle Region) (ABIN2776564)
Antigène
Voir toutes UPF3A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- QRYHVDDGRR HRAHHEPERL SRRSEDEQRW GKGPGQDRGK KGSQDSGAPG
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Homologie
- Human: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against UPF3A. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human UPF3A
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 476 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))
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Autre désignation
- UPF3A
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Sujet
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UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon j
Alias Symbols: HUPF3A, RENT3A, UPF3
Protein Interaction Partner: HTT, SMG1, HBB, APP, RNPS1, NXF1, SRRM1, TOPORS, PIGT, ALYREF, IFITM2, RBM8A, GSK3B, UPF1, UPF2, DCP2, UPF3B, EXOSC4, XRN1, EXOSC2, EXOSC10, PARN,
Protein Size: 476 -
Poids moléculaire
- 55 kDa
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ID gène
- 65110
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NCBI Accession
- NM_023011, NP_075387
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UniProt
- Q9H1J1
Antigène
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