HNRNPC anticorps (N-Term)

N° du produit ABIN2776586

Il existe 1 publication pour ce produit. L’anticorps anti-HNRNPC Polyclonal Lapin est utilisé pour la détection de HNRNPC dans des échantillons de Humain, Souris, Rat, Lapin, Chien et Porc. Il a été validé pour WB.

Aperçu rapide pour HNRNPC anticorps (N-Term) (ABIN2776586)

Antigène: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNRNPC est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HNRNPC anticorps

Épitope: N-Term

Fonction: HNRPC Antibody - N-terminal region

Séquence: LDINLAAEPK VNRGKAGVKR SAAEMYGSVT EHPSPSPLLS SSFDLDYDFQ

Homologie: Dog: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HNRPC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPC

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41037-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HNRNPC (ABIN2776586)

Hayakawa, Fujikane, Ito, Matsumoto, Nakayama, Sekiguchi: "Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress." dans: Biochemical and biophysical research communications, Vol. 403, Issue 2, pp. 220-4, (2010) (PubMed).

Détails sur HNRNPC

Antigène: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Autre désignation: HNRPC

Sujet:

Background Information: HNRPC belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein can act as a tetramer and is involved in the assembly of 40S hnRNP particles.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has one RRM domain that binds to RNAs. Two alternatively spliced transcript variants have been described for this gene.

Gene Name: Heterogeneous nuclear ribonucleoprotein C (C1/C2)

Alternative Symbols: C1, C2, HNRNP, HNRPC, SNRPC

Protein Name: Heterogeneous nuclear ribonucleoproteins C1/C2

Poids moléculaire: 33kDa

ID gène: 3183

NCBI Accession: NP_112604

UniProt: P07910