ERI1 anticorps (C-Term)
Aperçu rapide pour ERI1 anticorps (C-Term) (ABIN2776657)
Antigène
Voir toutes ERI1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- GSWDMSKFLN IQCQLSRLKY PPFAKKWINI RKSYGNFYKV PRSQTKLTIM
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against THEX1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human THEX1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 349 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ERI1 (Exoribonuclease 1 (ERI1))
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Autre désignation
- THEX1
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Sujet
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THEX1 contains 1 SAP domain and 1 exonuclease domain. It is an RNA exonuclease that binds to the 3' end of histone mRNAs and probably degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. It is also able to degrade the 3' overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi).
Alias Symbols: HEXO, THEX1, 3'HEXO
Protein Interaction Partner: UBC, HNRNPD, HHV8GK18_gp81, SLBP,
Protein Size: 349 -
Poids moléculaire
- 38 kDa
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ID gène
- 90459
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NCBI Accession
- NM_153332, NP_699163
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UniProt
- Q8IV48
Antigène
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