CDC25B anticorps (N-Term)

N° du produit ABIN2776752

Détail du produit anti-CDC25B anticorps

Antigène: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC25B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TQTMHDLAGL GSETPKSQVG TLLFRSRSRL THLSLSRRAS ESSLSSESSE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CDC25B. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CDC25B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 580 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDC25B

Antigène: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Autre désignation: CDC25B (CDC25B Produits)

Synonymes: anticorps CDC25B, anticorps AI604853, anticorps cell division cycle 25B, anticorps cdc25b, anticorps CDC25B, anticorps Cdc25b

Sujet: CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined.CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Protein Interaction Partner: BTRC, UBC, FBXW11, MAPK9, CDK5, CDK1, YWHAQ, MAPKAPK2, UBD, BRSK2, CDC14A, CDK2, Cdc25b, FOXM1, BRSK1, FHL3, KAT2B, MELK, YWHAE, CHEK1, AURKA, SFN, YWHAB, YWHAZ, MAPK14, CREBBP, AR, ESR1, CSNK2B, CSNK2A1, YWHAH, PGR, PHB2, KRT85, KRT35, KRT31,
Protein Size: 580

Poids moléculaire: 65 kDa

ID gène: 994

NCBI Accession: NM_021873, NP_068659

UniProt: P30305

Pathways: Cycle Cellulaire, M Phase, Autophagy