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UGT1A6 anticorps (C-Term)

UGT1A6 Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Mouton WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2776828
  • Antigène Voir toutes UGT1A6 Anticorps
    UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))
    Épitope
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 23
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Mouton
    Hôte
    • 20
    • 3
    Lapin
    Clonalité
    • 21
    • 2
    Polyclonal
    Conjugué
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UGT1A6 est non-conjugé
    Application
    • 10
    • 8
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    APHLRPAAHD LTWYQYHSLD VIGFLLAVVL TVAFITFKCC AYGYRKCLGK
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against UGT1A6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human UGT1A6
    Top Product
    Discover our top product UGT1A6 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 532 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))
    Autre désignation
    UGT1A6 (UGT1A6 Produits)
    Synonymes
    anticorps GNT1, anticorps HLUGP, anticorps HLUGP1, anticorps UDPGT, anticorps UDPGT 1-6, anticorps UGT1, anticorps UGT1A6S, anticorps UGT1F, anticorps UGT1A10, anticorps UGT1A6, anticorps UGT1A7, anticorps UGT1A8, anticorps UGT1A9, anticorps DKFZP469F071, anticorps UGT1A5, anticorps UGT, anticorps Udpgt, anticorps Ugt1, anticorps Ugt1a7, anticorps UGT1-06, anticorps UGT1.6, anticorps Ugt1a6b, anticorps Ugt1a6, anticorps UDP glucuronosyltransferase family 1 member A6, anticorps UDP glucuronosyltransferase family 1 member A1, anticorps UDP glucuronosyltransferase 1 family, polypeptide A6, anticorps UDP-glucuronosyltransferase 1-1, anticorps UDP glucuronosyltransferase 1 family, polypeptide A6 S homeolog, anticorps UDP-glucuronosyltransferase 1-6, anticorps UGT1A6, anticorps UGT1A1, anticorps LOC739942, anticorps ugt1a6.S, anticorps ugt1a6, anticorps LOC100481084, anticorps Ugt1a6, anticorps UGT1-6, anticorps LOC100731122
    Sujet
    UGT1A6 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.
    Alias Symbols: GNT1, HLUGP, HLUGP1, MGC29860, UDPGT, UGT1, UGT1F, UGT1A6S, UDPGT 1-6
    Protein Size: 532
    Poids moléculaire
    58 kDa
    ID gène
    54578
    NCBI Accession
    NM_001072, NP_001063
    UniProt
    P19224
    Pathways
    Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
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