Desmin anticorps (Middle Region)

N° du produit ABIN2776843

Cet anticorps Lapin Polyclonal détecte spécifiquement Desmin dans WB. Il présente une réactivité envers Humain, Rat, Souris, Chien, Boeuf (Vache), Lapin, Cheval et Cobaye.

Aperçu rapide pour Desmin anticorps (Middle Region) (ABIN2776843)

Antigène: Desmin (DES)

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Desmin anticorps

Épitope: Middle Region

Séquence: MALDVEIATY RKLLEGEESR INLPIQTYSA LNFRETSPEQ RGSEVHTKKT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DES. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human DES

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 470 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Desmin

Antigène: Desmin (DES)

Autre désignation: DES

Sujet: DES is a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in its gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
Protein Interaction Partner: PPP1R18, UBE2I, EHHADH, TRIM63, TRIM55, UBC, YWHAQ, MAPKAPK2, CAPN1, MLH1, AURKB, HADHB, MYL6, JUP, HSP90AA5P, HNRNPUL1, CCT7, SNRNP70, RPL29, RPL17, UBD, CRYAB, SHBG, SP1, ITSN1, NEB, PLEKHA5, SYNC, TRIM7, SYNM, ROCK1, PKD1, SPTAN1, S100B, S100A1, DSP,
Protein Size: 470

Poids moléculaire: 53 kDa

ID gène: 1674

NCBI Accession: NM_001927, NP_001918

UniProt: P17661