Complement C2 anticorps (N-Term)

N° du produit ABIN2776929

Cet anticorps Lapin Polyclonal détecte spécifiquement Complement C2 dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Chien, Cheval, Porc, Boeuf (Vache), Lapin et Cobaye.

Aperçu rapide pour Complement C2 anticorps (N-Term) (ABIN2776929)

Antigène: Complement C2

Reactivité: Humain, Rat, Souris, Chien, Cheval, Porc, Boeuf (Vache), Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement C2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Complement C2 anticorps

Épitope: N-Term

Fonction: C2 Antibody - N-terminal region

Séquence: EPICRQPYSY DFPEDVAPAL GTSFSHMLGA TNPTQKTKES LGRKIQIQRS

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against C2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human C2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41668-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Complement C2

Antigène: Complement C2

Autre désignation: C2

Sujet:

Background Information: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

Gene Name: complement C2

Alternative Symbols: CO2, ARMD14

Protein Name: complement C2

Poids moléculaire: 81kDa

ID gène: 717

NCBI Accession: NP_000054

UniProt: P06681