GAMT anticorps (N-Term)
Aperçu rapide pour GAMT anticorps (N-Term) (ABIN2776937)
Antigène
Voir toutes GAMT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MSAPSATPIF APGENCSPAW GAAPAAYDAA DTHLRILGKP VMERWETPYM
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Homologie
- Cow: 92%, Guinea Pig: 85%, Human: 100%, Mouse: 92%, Pig: 92%, Rat: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against GAMT. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human GAMT
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 236 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
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Autre désignation
- GAMT
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Sujet
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GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals.The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: PIG2, TP53I2
Protein Interaction Partner: FOS, CSNK2B, UBC, TERF2IP, POT1, TERF1,
Protein Size: 236 -
Poids moléculaire
- 26 kDa
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ID gène
- 2593
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NCBI Accession
- NM_000156, NP_000147
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UniProt
- Q14353
Antigène
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