PKLR anticorps (N-Term)

N° du produit ABIN2776945

L’anticorps anti-PKLR Polyclonal Lapin est utilisé pour la détection de PKLR dans des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval, Porc et Poisson zèbre (Danio rerio). Il a été validé pour WB et IHC.

Aperçu rapide pour PKLR anticorps (N-Term) (ABIN2776945)

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Lapin, Cheval, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKLR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PKLR anticorps

Épitope: N-Term

Fonction: PKLR Antibody - N-terminal region

Séquence: STSIIATIGP ASRSVERLKE MIKAGMNIAR LNFSHGSHEY HAESIANVRE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PKLR. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PKLR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8109754

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PKLR

Antigène: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Autre désignation: PKLR

Sujet:

Background Information: PKLR is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).The protein encoded by this gene is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene Name: Pyruvate kinase, liver and RBC

Alternative Symbols: PK1, PKL, RPK, PKRL

Protein Name: Pyruvate kinase isozymes R/L

Poids moléculaire: 58kDa

ID gène: 5313

NCBI Accession: NP_870986

UniProt: P30613

Pathways: Ribonucleoside Biosynthetic Process