HSD17B1 anticorps (N-Term)

N° du produit ABIN2776958

Cité dans 1 publication. Cet anticorps anti-HSD17B1 Polyclonal Lapin (ABIN2776958) détecte spécifiquement HSD17B1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Porc, Cobaye et Lapin.

Aperçu rapide pour HSD17B1 anticorps (N-Term) (ABIN2776958)

Antigène: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Porc, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HSD17B1 anticorps

Épitope: N-Term

Fonction: HSD17B1 Antibody - N-terminal region

Séquence: MARTVVLITG CSSGIGLHLA VRLASDPSQS FKVYATLRDL KTQGRLWEAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HSD17B1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HSD17B1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102873

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HSD17B1 (ABIN2776958)

Tsuchiya, Nakao, Katoh, Sasaki, Hiroshima, Tanaka, Matsunaga, Hanaoka, Tsugane, Ikenoue: "Association between endometriosis and genetic polymorphisms of the estradiol-synthesizing enzyme genes HSD17B1 and CYP19." dans: Human reproduction (Oxford, England), Vol. 20, Issue 4, pp. 974-8, (2005) (PubMed).

Détails sur HSD17B1

Antigène: HSD17B1 (Hydroxysteroid (17-Beta) Dehydrogenase 1 (HSD17B1))

Autre désignation: HSD17B1

Sujet:

Background Information: HSD17B1 is favors the reduction of estrogens and androgens. It also has 20-alpha-HSD activity. It uses preferentially NADH.

Gene Name: Hydroxysteroid (17-beta) dehydrogenase 1

Alternative Symbols: E2DH, HSD17, EDHB17, EDH17B2, SDR28C1, 17-beta-HSD, 20-alpha-HSD

Protein Name: Estradiol 17-beta-dehydrogenase 1

Poids moléculaire: 36kDa

ID gène: 3292

NCBI Accession: NP_000404

UniProt: P14061

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis