HSD3B1 anticorps (N-Term)

N° du produit ABIN2777011

Cité dans 1 publication. Cet anticorps anti-HSD3B1 Polyclonal Lapin (ABIN2777011) détecte spécifiquement HSD3B1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Porc, Mouton, Boeuf (Vache), Chévre et Cheval.

Aperçu rapide pour HSD3B1 anticorps (N-Term) (ABIN2777011)

Antigène: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Reactivité: Humain, Rat, Porc, Mouton, Boeuf (Vache), Chévre, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD3B1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HSD3B1 anticorps

Épitope: N-Term

Séquence: TGWSCLVTGA GGFLGQRIIR LLVKEKELKE IRVLDKAFGP ELREEFSKLQ

Homologie: Cow: 79%, Goat: 82%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 79%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against HSD3B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HSD3B1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 373 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HSD3B1 (ABIN2777011)

Mirkheshti, Park, Jiang, Cropper, Werner, Song, Chatterjee: "Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer." dans: Oncotarget, Vol. 7, Issue 38, pp. 62240-62254, (2016) (PubMed).

Détails sur HSD3B1

Antigène: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Autre désignation: HSD3B1

Sujet: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Alias Symbols: HSD3B, HSDB3, I, HSDB3A, SDR11E1, 3BETAHSD
Protein Size: 373

Poids moléculaire: 42 kDa

ID gène: 3283

NCBI Accession: NM_000862, NP_000853

UniProt: P14060

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis