HSD3B1 anticorps (Internal Region)

N° du produit ABIN6262381

Détail du produit anti-HSD3B1 anticorps

Antigène: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Épitope: Internal Region

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD3B1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: HSD3B1 Antibody detects endogenous levels of total HSD3B1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HSD3B1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur HSD3B1

Antigène: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Autre désignation: HSD3B1 (HSD3B1 Produits)

Synonymes: anticorps 3BETAHSD, anticorps HSD3B, anticorps HSDB3, anticorps HSDB3A, anticorps I, anticorps SDR11E1, anticorps HSD3B1, anticorps MGC131206, anticorps D3Ertd383e, anticorps 3B-HSD, anticorps 3BHSD, anticorps si:rp71-68n21.10, anticorps hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1, anticorps 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, anticorps hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 L homeolog, anticorps HSD3B1, anticorps LOC469446, anticorps LOC713091, anticorps hsd3b1.L, anticorps LOC100451655, anticorps Hsd3b1, anticorps hsd3b1

Sujet:

Description: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta5-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone.

Gene: HSD3B1

Poids moléculaire: 42 kDa

ID gène: 3283

UniProt: P14060

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis