HSD3B1 anticorps (N-Term)

N° du produit ABIN2777011

Détail du produit anti-HSD3B1 anticorps

Antigène: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Épitope: N-Term

Reactivité: Humain, Rat, Porc, Mouton, Boeuf (Vache), Chévre, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD3B1 est non-conjugé

Application: Western Blotting (WB)

Séquence: TGWSCLVTGA GGFLGQRIIR LLVKEKELKE IRVLDKAFGP ELREEFSKLQ

Homologie: Cow: 79%, Goat: 82%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 79%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against HSD3B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HSD3B1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 373 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HSD3B1 (ABIN2777011)

Mirkheshti, Park, Jiang, Cropper, Werner, Song, Chatterjee: "Dual targeting of androgen receptor and mTORC1 by salinomycin in prostate cancer." dans: Oncotarget, Vol. 7, Issue 38, pp. 62240-62254, (2016) (PubMed).

Détails sur HSD3B1

Antigène: HSD3B1 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 1 (HSD3B1))

Autre désignation: HSD3B1 (HSD3B1 Produits)

Synonymes: anticorps 3BETAHSD, anticorps HSD3B, anticorps HSDB3, anticorps HSDB3A, anticorps I, anticorps SDR11E1, anticorps HSD3B1, anticorps MGC131206, anticorps D3Ertd383e, anticorps 3B-HSD, anticorps 3BHSD, anticorps si:rp71-68n21.10, anticorps hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1, anticorps 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, anticorps hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 L homeolog, anticorps HSD3B1, anticorps LOC469446, anticorps LOC713091, anticorps hsd3b1.L, anticorps LOC100451655, anticorps Hsd3b1, anticorps hsd3b1

Sujet: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Alias Symbols: HSD3B, HSDB3, I, HSDB3A, SDR11E1, 3BETAHSD
Protein Size: 373

Poids moléculaire: 42 kDa

ID gène: 3283

NCBI Accession: NM_000862, NP_000853

UniProt: P14060

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis