Prostate Specific Antigen anticorps (Middle Region)
Aperçu rapide pour Prostate Specific Antigen anticorps (Middle Region) (ABIN2777044)
Antigène
Voir toutes Prostate Specific Antigen (PSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- LRPGDDSSHD LMLLRLSEPA ELTDAVKVMD LPTQEPALGT TCYASGWGSI
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Homologie
- Dog: 77%, Human: 100%, Mouse: 86%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against KLK3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 261 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip." dans: Biosensors & bioelectronics, Vol. 77, pp. 491-8, (2015) (PubMed).
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: "Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip." dans: Biosensors & bioelectronics, Vol. 77, pp. 491-8, (2015) (PubMed).
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- Prostate Specific Antigen (PSA)
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Autre désignation
- KLK3
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Sujet
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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Alias Symbols: APS, KLK2A1, PSA, hK3
Protein Interaction Partner: ALB, PZP, SERPINA5, SERPINA1, SEMG2, SEMG1, PLG, PTHLH, IGFBP3, FN1, EPOR, SLPI, SERPINA3, A2M, POLR2A, AR, KAT5, RUVBL1, CTNNB1,
Protein Size: 261 -
Poids moléculaire
- 26 kDa
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ID gène
- 354
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NCBI Accession
- NM_001648, NP_001639
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UniProt
- P07288
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Pathways
- Système du Complément
Antigène
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