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ALOX15B anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-ALOX15B a été validé pour WB. Il convient pour détecter ALOX15B dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Cheval, Lapin, Chien et Cobaye. Il y a 1 publication disponible.
N° du produit ABIN2777053

Aperçu rapide pour ALOX15B anticorps (C-Term) (ABIN2777053)

Antigène

Voir toutes ALOX15B Anticorps
ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Reactivité

  • 33
  • 19
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Humain, Rat, Souris, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye

Hôte

  • 46
  • 2
Lapin

Clonalité

  • 46
  • 2
Polyclonal

Conjugué

  • 24
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ALOX15B est non-conjugé

Application

  • 21
  • 15
  • 13
  • 13
  • 9
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Séquence

    ATCEGFIATL PPVNATCDVI LALWLLSKEP GDQRPLGTYP DEHFTEEAPR

    Homologie

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

    Attributs du produit

    This is a rabbit polyclonal antibody against ALOX15B. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human ALOX15B
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 676 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Subbarayan, Xu, Kim, Yang, Hoque, Sabichi, Llansa, Mendoza, Logothetis, Newman, Lippman, Menter: "Inverse relationship between 15-lipoxygenase-2 and PPAR-gamma gene expression in normal epithelia compared with tumor epithelia." dans: Neoplasia (New York, N.Y.), Vol. 7, Issue 3, pp. 280-93, (2005) (PubMed).

  • Antigène

    ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

    Autre désignation

    ALOX15B

    Sujet

    ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively.This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
    Alias Symbols: 15-LOX-2
    Protein Interaction Partner: RXRA, PPARG, ERAL1,
    Protein Size: 676

    Poids moléculaire

    74 kDa

    ID gène

    247

    NCBI Accession

    NM_001141, NP_001132

    UniProt

    O15296
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