ALOX15B anticorps (C-Term)

N° du produit ABIN2777053

Détail du produit anti-ALOX15B anticorps

Antigène: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX15B est non-conjugé

Application: Western Blotting (WB)

Séquence: ATCEGFIATL PPVNATCDVI LALWLLSKEP GDQRPLGTYP DEHFTEEAPR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ALOX15B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ALOX15B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 676 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ALOX15B (ABIN2777053)

Subbarayan, Xu, Kim, Yang, Hoque, Sabichi, Llansa, Mendoza, Logothetis, Newman, Lippman, Menter: "Inverse relationship between 15-lipoxygenase-2 and PPAR-gamma gene expression in normal epithelia compared with tumor epithelia." dans: Neoplasia (New York, N.Y.), Vol. 7, Issue 3, pp. 280-93, (2005) (PubMed).

Détails sur ALOX15B

Antigène: ALOX15B (Arachidonate 15-Lipoxygenase B (ALOX15B))

Autre désignation: ALOX15B (ALOX15B Produits)

Synonymes: anticorps 15-LOX-2, anticorps ALOX15B, anticorps arachidonate 15-lipoxygenase, type B, anticorps arachidonate 15-lipoxygenase B, anticorps ALOX15B, anticorps Alox15b, anticorps LOC100525835

Sujet: ALOX15B is a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively.This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: 15-LOX-2
Protein Interaction Partner: RXRA, PPARG, ERAL1,
Protein Size: 676

Poids moléculaire: 74 kDa

ID gène: 247

NCBI Accession: NM_001141, NP_001132

UniProt: O15296