Chromogranin A anticorps (N-Term)

N° du produit ABIN2777070

L’anticorps anti-Chromogranin A Polyclonal Lapin est utilisé pour la détection de Chromogranin A dans des échantillons de Humain, Rat, Souris, Porc, Boeuf (Vache), Cheval et Chien. Il a été validé pour WB.

Aperçu rapide pour Chromogranin A anticorps (N-Term) (ABIN2777070)

Antigène: Chromogranin A (CHGA)

Reactivité: Humain, Rat, Souris, Porc, Boeuf (Vache), Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Chromogranin A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Chromogranin A anticorps

Épitope: N-Term

Fonction: CHGA Antibody - N-terminal region

Séquence: PVSQECFETL RGDERILSIL RHQNLLKELQ DLALQGAKER AHQQKKHSGF

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CHGA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CHGA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097028

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Chromogranin A

Antigène: Chromogranin A (CHGA)

Autre désignation: CHGA

Sujet:

Background Information: CHGA is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. Its gene?s product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

Gene Name: Chromogranin A (parathyroid secretory protein 1)

Alternative Symbols: CGA

Protein Name: Chromogranin-A

Poids moléculaire: 51kDa

ID gène: 1113

NCBI Accession: NP_001266

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling