PLAP anticorps (C-Term)

N° du produit ABIN2777088

Cet anticorps Lapin Polyclonal détecte spécifiquement PLAP dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval et Poisson zèbre (Danio rerio) et a été mentionné dans 1 publication.

Aperçu rapide pour PLAP anticorps (C-Term) (ABIN2777088)

Antigène: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PLAP anticorps

Épitope: C-Term

Séquence: TVLLYGNGPG YVLKDGARPD VTESESGSPE YRQQSAVPLD EETHAGEDVA

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ALPP. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ALPP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 535 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PLAP (ABIN2777088)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Détails sur PLAP

Antigène: PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))

Autre désignation: ALPP

Sujet: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. ALPP is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form.There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Alias Symbols: ALP, PLAP, PALP
Protein Interaction Partner: COL2A1, KRTAP10-3, KRTAP4-12, KRTAP5-9, RPA3, RPA2, RPA1, FBXO6, LATS1, UBC, SUMO1, SUMO2, UBXN6, Cep76, Trim69, Erh, Cbx1, UBXN11, ASPSCR1, NSFL1C, UBXN1, UBXN7, FAF2, FAF1, ALPP, PIGK, GPLD1,
Protein Size: 535

Poids moléculaire: 59 kDa

ID gène: 250

NCBI Accession: NM_001632, NP_001623

UniProt: P05187