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DLAT anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement DLAT dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye et Cheval.
N° du produit ABIN2777101

Aperçu rapide pour DLAT anticorps (N-Term) (ABIN2777101)

Antigène

Voir toutes DLAT Anticorps
DLAT (Dihydrolipoyl Transacetylase (DLAT))

Reactivité

  • 60
  • 25
  • 21
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain, Souris, Rat, Lapin, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Cobaye, Cheval

Hôte

  • 57
  • 7
Lapin

Clonalité

  • 55
  • 9
Polyclonal

Conjugué

  • 37
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Cet anticorp DLAT est non-conjugé

Application

  • 46
  • 26
  • 22
  • 14
  • 13
  • 12
  • 11
  • 4
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    WTPSSGATPR NRLLLQLLGS PGRRYYSLPP HQKVPLPSLS PTMQAGTIAR

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against DLAT. It was validated on Western Blot and immunohistochemistry.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the N terminal region of human DLAT
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 647 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    DLAT (Dihydrolipoyl Transacetylase (DLAT))

    Autre désignation

    DLAT

    Sujet

    DLAT is dihydrolipoamide acetyltransferase, the E2 subunit of the mammalian pyruvate dehydrogenase complex of the inner mitochondrial membrane. Patients with primary biliary cirrhosis show autoantibodies to DLAT.The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC, EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC, MIM 109720) show autoantibodies to DLAT.[supplied by OMIM].
    Alias Symbols: DLTA, PDC-E2, PDCE2
    Protein Interaction Partner: MDM2, UBC, ADRB2, PRKD3, PDHX, MMGT1, MRPL1, ACAD9, SYNCRIP, PDHA2, PDHA1, OGDH, NDUFS4, HSPA1L, DLD, COX5B, COPS5, CUL1, SIRT7, TSG101, KIAA0101, PSMA3, PDK4, PDK3, PDK2, PDK1, PDHB,
    Protein Size: 647

    Poids moléculaire

    69 kDa

    ID gène

    1737

    NCBI Accession

    NM_001931, NP_001922

    UniProt

    P10515
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