DLAT anticorps (C-Term)
Aperçu rapide pour DLAT anticorps (C-Term) (ABIN2777102)
Antigène
Voir toutes DLAT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- DVVSLATKAR EGKLQPHEFQ GGTFTISNLG MFGIKNFSAI INPPQACILA
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Homologie
- Dog: 100%, Human: 100%, Mouse: 100%, Pig: 92%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against DLAT. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human DLAT
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 647 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DLAT (Dihydrolipoyl Transacetylase (DLAT))
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Autre désignation
- DLAT
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Sujet
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DLAT is dihydrolipoamide acetyltransferase, the E2 subunit of the mammalian pyruvate dehydrogenase complex of the inner mitochondrial membrane. Patients with primary biliary cirrhosis show autoantibodies to DLAT.The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC, EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC, MIM 109720) show autoantibodies to DLAT.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2696 AK057299.1 1-2696 2697-3933 BC039084.1 2066-3302 3934-4322 DB551427.1 98-486
Alias Symbols: DLTA, PDC-E2, PDCE2
Protein Interaction Partner: MDM2, UBC, ADRB2, PRKD3, PDHX, MMGT1, MRPL1, ACAD9, SYNCRIP, PDHA2, PDHA1, OGDH, NDUFS4, HSPA1L, DLD, COX5B, COPS5, CUL1, SIRT7, TSG101, KIAA0101, PSMA3, PDK4, PDK3, PDK2, PDK1, PDHB,
Protein Size: 647 -
Poids moléculaire
- 69 kDa
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ID gène
- 1737
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NCBI Accession
- NM_001931, NP_001922
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UniProt
- Q86YI5
Antigène
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