MMP1 anticorps (N-Term)

N° du produit ABIN2777119

Cet anticorps Lapin Polyclonal détecte spécifiquement MMP1 dans WB et IHC. Il présente une réactivité envers Humain et Cheval.

Aperçu rapide pour MMP1 anticorps (N-Term) (ABIN2777119)

Antigène: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Reactivité: Humain, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MMP1 anticorps

Épitope: N-Term

Séquence: PATLETQEQD VDLVQKYLEK YYNLKNDGRQ VEKRRNSGPV VEKLKQMQEF

Homologie: Horse: 77%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MMP1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MMP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 469 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MMP1

Antigène: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Autre désignation: MMP1

Sujet: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP1 is a secreted enzyme which breaks down the interstitial collagens, types I, II, and III.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Alias Symbols: CLG, CLGN
Protein Interaction Partner: SOX8, UBC, TNFSF11, CCL13, BCAN, TIMP1, ITGA2, MMP7, CCL7, CCL2, ACAN, TFPI, IGFBP3, COL2A1, CMA1, BSG, SERPINA3, CD44, F2R,
Protein Size: 469

Poids moléculaire: 54 kDa

ID gène: 4312

NCBI Accession: NM_002421, NP_002412

UniProt: P03956