Stanniocalcin 1 anticorps (N-Term)

N° du produit ABIN2777144

Cet anticorps Lapin Polyclonal détecte spécifiquement Stanniocalcin 1 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cheval, Chien, Porc, Boeuf (Vache), Cobaye et Lapin et a été mentionné dans 1 publication.

Aperçu rapide pour Stanniocalcin 1 anticorps (N-Term) (ABIN2777144)

Antigène: Stanniocalcin 1 (STC1)

Reactivité: Humain, Souris, Rat, Cheval, Chien, Porc, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Stanniocalcin 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Stanniocalcin 1 anticorps

Épitope: N-Term

Séquence: MLQNSAVLLV LVISASATHE AEQNDSVSPR KSRVAAQNSA EVVRCLNSAL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against STC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human STC1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 247 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Stanniocalcin 1 (ABIN2777144)

Gao, Xu, Chen, Wang, Wang, Wu, Yuan: "Potential protein toxicity of synthetic pigments: binding of poncean S to human serum albumin." dans: Biophysical journal, Vol. 94, Issue 3, pp. 906-17, (2008) (PubMed).

Détails sur Stanniocalcin 1

Antigène: Stanniocalcin 1 (STC1)

Autre désignation: STC1

Sujet: STC1 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. It contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate.This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: STC
Protein Size: 247

Poids moléculaire: 26 kDa

ID gène: 6781

NCBI Accession: NM_003155, NP_003146

UniProt: P52823

Pathways: Hormone Activity