LEFTY2 anticorps (N-Term)

N° du produit ABIN2777146

Cet anticorps Lapin Polyclonal détecte spécifiquement LEFTY2 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Porc, Boeuf (Vache) et Cheval.

Aperçu rapide pour LEFTY2 anticorps (N-Term) (ABIN2777146)

Antigène: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LEFTY2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-LEFTY2 anticorps

Épitope: N-Term

Fonction: LEFTY2 Antibody - N-terminal region

Séquence: MWPLWLCWAL WVLPLAGPGA ALTEEQLLGS LLRQLQLSEV PVLDRADMEK

Homologie: Cow: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against LEFTY2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LEFTY2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42107-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur LEFTY2

Antigène: LEFTY2 (Left-Right Determination Factor 2 (LEFTY2))

Autre désignation: LEFTY2

Sujet:

Background Information: LEFTY2 is a member of the TGF-beta family of proteins. The protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in its gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of its gene in the endometrium.This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.

Gene Name: Left-right determination factor 2

Alternative Symbols: EBAF, LEFTA, TGFB4, LEFTYA

Protein Name: Left-right determination factor 2

Poids moléculaire: 40kDa

ID gène: 7044

NCBI Accession: NP_003231

UniProt: O00292