CBFB anticorps (N-Term)

N° du produit ABIN2777178

L’anticorps Lapin Polyclonal anti-CBFB a été validé pour WB. Il convient pour détecter CBFB dans des échantillons de Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval, Porc, Chien, Lapin, Cobaye et Saccharomyces cerevisiae.

Aperçu rapide pour CBFB anticorps (N-Term) (ABIN2777178)

Antigène: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Cheval, Porc, Chien, Lapin, Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBFB est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CBFB anticorps

Épitope: N-Term

Séquence: MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CBFB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CBFB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 182 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CBFB

Antigène: CBFB (Core-Binding Factor, beta Subunit (CBFB))

Autre désignation: CBFB

Sujet: CBFB encodes a protein that is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.
Alias Symbols: PEBP2B
Protein Interaction Partner: vif, CUL5, UBC, RAB2A, MYC, nef, APOBEC3G, RUNX1, ELAVL1, KMT2A, COPRS, RUNX3, MYOD1, CHGB, CBFA2T2, RUNX2, CBFB, C1QBP,
Protein Size: 182

Poids moléculaire: 21 kDa

ID gène: 865

NCBI Accession: NM_001755, NP_001746

UniProt: Q13951

Pathways: Regulation of Lipid Metabolism by PPARalpha