CBFB anticorps (N-Term)
-
- Antigène Voir toutes CBFB Anticorps
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
-
Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Poisson zèbre (Danio rerio), Cheval, Boeuf (Vache), Chien, Porc, Lapin, Cobaye, Saccharomyces cerevisiae
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CBFB est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- MPRVVPDQRS KFENEEFFRK LSRECEIKYT GFRDRPHEER QARFQNACRD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CBFB. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CBFB
- Top Product
- Discover our top product CBFB Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 182 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
- Autre désignation
- CBFB (CBFB Produits)
- Synonymes
- anticorps PEBP2B, anticorps Cbfb, anticorps pebp2b, anticorps Pebp2, anticorps CBFB, anticorps unp1266, anticorps cbf-beta, anticorps cbfbeta, anticorps pea2-beta, anticorps pebp2-beta, anticorps AI893578, anticorps PEA2, anticorps PEBP2b, anticorps Pebpb2, anticorps core-binding factor beta subunit, anticorps core binding factor beta subunit, anticorps core-binding factor, beta subunit, anticorps core-binding factor, beta subunit S homeolog, anticorps core binding factor beta, anticorps CBFB, anticorps Cbfb, anticorps cbfb, anticorps cbfb.S
- Sujet
-
CBFB encodes a protein that is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.
Alias Symbols: PEBP2B
Protein Interaction Partner: vif, CUL5, UBC, RAB2A, MYC, nef, APOBEC3G, RUNX1, ELAVL1, KMT2A, COPRS, RUNX3, MYOD1, CHGB, CBFA2T2, RUNX2, CBFB, C1QBP,
Protein Size: 182 - Poids moléculaire
- 21 kDa
- ID gène
- 865
- NCBI Accession
- NM_001755, NP_001746
- UniProt
- Q13951
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
-