LMO2 anticorps (N-Term)
Aperçu rapide pour LMO2 anticorps (N-Term) (ABIN2777181)
Antigène
Voir toutes LMO2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- RKSLDPSEEP VDEVLQIPPS LLTCGGCQQN IGDRYFLKAI DQYWHEDCLS
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against LMO2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human LMO2
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))
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Autre désignation
- LMO2
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Sujet
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LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: RBTN2, RBTNL1, RHOM2, TTG2
Protein Interaction Partner: ADAMTSL4, MBIP, HOOK1, TFPT, NOTCH2NL, KRTAP10-7, CCDC36, NUTM1, SPERT, FAM154A, CLHC1, KRT40, SSX2IP, CMTM5, MRFAP1L1, IFT43, C1orf94, LZTS2, TSC22D4, DBF4B, CCDC33, RINT1, NIF3L1, TRIM54, AGTRAP, ZFP64, BANP, STAT3, STAT1, SOX5, SKP1, ROCK1, REL, PRKG1,
Protein Size: 227 -
Poids moléculaire
- 24 kDa
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ID gène
- 4005
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NCBI Accession
- NM_005574, NP_005565
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Pathways
- Chromatin Binding
Antigène
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