MYB anticorps (C-Term)

N° du produit ABIN2777183

Détail du produit anti-MYB anticorps

Antigène: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Épitope: C-Term

Reactivité: Humain, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYB est non-conjugé

Application: Western Blotting (WB)

Séquence: VPKNRSLASP LQPCSSTWEP ASCGKMEEQM TSSSQARKYV NAFSARTLVM

Homologie: Dog: 80%, Human: 100%, Pig: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MYB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MYB

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MYB

Antigène: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Autre désignation: MYB (MYB Produits)

Synonymes: anticorps Cmyb, anticorps c-myb, anticorps c-myb_CDS, anticorps efg, anticorps AI550390, anticorps M16449, anticorps cmyb, anticorps xmyb, anticorps MYB proto-oncogene, transcription factor, anticorps myeloblastosis oncogene, anticorps MYB proto-oncogene, transcription factor S homeolog, anticorps v-myb avian myeloblastosis viral oncogene homolog, anticorps MYB, anticorps Myb, anticorps myb.S, anticorps myb

Sujet: This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
Alias Symbols: Cmyb, c-myb, c-myb_CDS, efg
Protein Interaction Partner: UBC, ERC2, UPF2, PPM1K, MYOZ2, SUMO1, SUMO2, CCND3, EP300, RBX1, FBXW5, PIAS1, CUL4A, UBE2I, DDB1, TRAF6, STAT5A, GATA3, KAT5, Fbxw7, CREBBP, LEF1, RPL4, KAT2B, CHD3, SIN3A, TRIM28, NCOR1, SKI, HIPK2, NLK, SP100, HLF, PARP1, ASH2L, RBBP5, KMT2A, MEN1, WDR
Protein Size: 640

Poids moléculaire: 70 kDa

ID gène: 4602

NCBI Accession: NM_005375, NP_005366

UniProt: P10242

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process