MYB anticorps (Sumoylation Site)
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- Antigène Voir toutes MYB Anticorps
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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Épitope
- AA 506-534, Sumoylation Site
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MYB est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This Myb Sumoylation Site antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from human Myb Sumoylation Site.
- Clone
- RB2559
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MYB Anticorps primaire
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- Indications d'application
- WB: 1:1000. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.
- Date de péremption
- 6 months
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- Antigène
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
- Autre désignation
- Myb (MYB Produits)
- Synonymes
- anticorps Cmyb, anticorps c-myb, anticorps c-myb_CDS, anticorps efg, anticorps AI550390, anticorps M16449, anticorps cmyb, anticorps xmyb, anticorps MYB proto-oncogene, transcription factor, anticorps myeloblastosis oncogene, anticorps MYB proto-oncogene, transcription factor S homeolog, anticorps v-myb avian myeloblastosis viral oncogene homolog, anticorps MYB, anticorps Myb, anticorps myb.S, anticorps myb
- Sujet
- Myb is a transcriptional activator, DNA-binding protein that recognizes the sequence 5'-YAAC[GT]G-3'. It participates in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed predominantly in haematopoietic cells and immature gastroepithelial cells. TRAF7 stimulates the sumoylation of Myb at Lys-523 and Lys-499, which are the same sites as those used for PIASy-induced sumoylation. A correlation has been established between reduction in sumoylation of Myb and increase in transcriptional activation. Negative influence on transactivation properties by the negative regulatory domain region of c-Myb depends on upon sumoylation.
- Poids moléculaire
- 72341
- NCBI Accession
- NP_001123644, NP_001123645, NP_001155128, NP_001155129, NP_001155130, NP_001155131, NP_001155132, NP_005366
- UniProt
- P10242
- Pathways
- Chromatin Binding, Positive Regulation of Immune Effector Process
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