ZEB1 anticorps (N-Term)

N° du produit ABIN2777193

Cet anticorps anti-ZEB1 est un anticorps Lapin Polyclonal détectant ZEB1 dans WB et IHC. Adapté pour Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Porc et Poisson zèbre (Danio rerio). Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour ZEB1 anticorps (N-Term) (ABIN2777193)

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reactivité: Humain, Souris, Rat, Lapin, Chien, Boeuf (Vache), Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZEB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ZEB1 anticorps

Épitope: N-Term

Séquence: NPRRNNVTNY NTVVETNSDS DDEDKLHIVE EESVTDAADC EGVPEDDLPT

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ZEB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ZEB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1124 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ZEB1 (ABIN2777193)

Kothandaraman, Bajic, Brendan, Huak, Keow, Razvi, Salto-Tellez, Choolani: "E2F5 status significantly improves malignancy diagnosis of epithelial ovarian cancer." dans: BMC cancer, Vol. 10, pp. 64, (2010) (PubMed).

Li, Xia, Huang, Chen, Su, Li, Wang, Ding, Shao: "A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells." dans: FEBS letters, Vol. 584, Issue 14, pp. 3198-202, (2010) (PubMed).

Détails sur ZEB1

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Autre désignation: ZEB1

Sujet: ZEB1 is a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site.
Alias Symbols: AREB6, BZP, DELTA-EF1, FECD6, MGC133261, NIL-2-A, NIL-2A, NIL2A, TCF8, ZEB, ZFHEP, ZFHX1A, PPCD3, DELTAEF1
Protein Interaction Partner: SUMO1, CDK6, GTF2A1, UBR4, SUMO2, SIRT1, SOX2, CTBP2, CTBP1, SMAD7, SMAD6, SMARCA4, SERPINH1, SMAD3, EP300, DRAP1, KAT5, SMAD2, SMAD1, CDH1,
Protein Size: 1124

Poids moléculaire: 124 kDa

ID gène: 6935

NCBI Accession: NM_030751, NP_110378

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation