HNF1A anticorps (C-Term)

N° du produit ABIN2777209

Cet anticorps Lapin Polyclonal détecte spécifiquement HNF1A dans WB. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cobaye, Cheval et Boeuf (Vache).

Aperçu rapide pour HNF1A anticorps (C-Term) (ABIN2777209)

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF1A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HNF1A anticorps

Épitope: C-Term

Séquence: QTMLITDTTN LSALASLTPT KQVFTSDTEA SSESGLHTPA SQATTLHVPS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HNF1A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human HNF1A

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HNF1A

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Autre désignation: HNF1A

Sujet: The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: HNF1, LFB1, TCF1, MODY3, TCF-1, HNF-1A, IDDM20
Protein Size: 452

Poids moléculaire: 49 kDa

ID gène: 6927

NCBI Accession: NM_000545, NP_000536

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis